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Heart Failure

TÍTULO:

A Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared with Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients with Heart Failure and Impaired Kidney Function

INFORMATION:

Sponsor:

Principal Investigator:

Therapeutic area:

Location:

Who can participate?*

AstraZeneca

Dr. Marco Alejandro Reza Orozco, Cardiólogo

Cardiología

Cd. Chihuahua, México.

You could participate if:

✔️ You have been diagnosed with heart failure and have symptoms such as fatigue, shortness of breath, or swelling.

✔️ In the last 6 months:

  • You were hospitalized due to worsening heart failure, or

  • You went to the emergency room for this reason and received intravenous treatment.

✔️ You are currently undergoing medical treatment for your heart, but you cannot use certain medications such as mineralocorticoid receptor antagonists (due to medical advice, side effects, or low kidney function).

✔️ Your kidneys are functioning at a reduced but stable level (your doctor has told you that you have reduced kidney function).

✔️ You are 18 years of age or older.

​​You may not be able to participate if: 

✖️ You have had a heart attack, stroke, or major heart surgery in the last 3 months.

✖️ You are on the waiting list for a heart transplant or use cardiac assist devices.

✖️ You have severe liver disease, active cancer undergoing treatment, or a medical condition that significantly limits your life expectancy.

✖️ You have type 1 diabetes.

✖️ You have recently had COVID-19 (in the last 4 weeks) or were hospitalized for this reason in the last 3 months.

*These points are for guidance only. Final eligibility is determined by medical evaluation and review of clinical studies. 
If you have any questions about any of the criteria, please do not hesitate to contact us and we will be happy to assist you.

What does participation involve?

If you are a candidate and decide to participate, the study may include:

🩺 Specialized medical evaluations

  • Detailed review of your medical history.

  • Physical examination.

  • Tests such as electrocardiogram, echocardiogram, and blood tests.

  • Regular monitoring of your heart and kidney function.

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💊 Treatment under medical supervisation

  • You will receive the study treatment or the corresponding comparator.

  • The entire process will be supervised by physicians specializing in heart failure.

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📅 Scheduled visits

  • You will attend regular appointments at our center.

  • Some visits may include blood sampling and adjustments to your treatment according to protocol.

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🔍 Continous monitoring

  • Your health will be carefully monitored throughout the study.

  • You can report any symptoms or concerns at any time.

 

💰 No cost to you

  • Consultations and studies related to the protocol are free of charge.

  • In some cases, transportation assistance may be available (depending on the study).

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Participation in a Clinical Trial is completely volundaty.

You can withdraw at any time if you choose to do so.

See our privace notice here

Or you can call the following numbers for mor information:

(614) 674 0705

(614) 222 0966

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© 2026 Mediadvance Clinical S.A.P.I. de C.V.

Antonio de Montes, 3714 Col. Parques de San Felipe

Chihuahua, Chih. MX

Tel:  +52 1 (614) 674 0705

 Fax +52 1 (614) 674 0706

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